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Q: What does it mean if cylinder 2 and 6 are not firing and it is not the plug, plug wire, or coil because they have all been changed.

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The van was really missing bad, would not pull hills unless you gained speed first. If you got over 60-70 miles per hour if will almost cut completely out. We put the hand held computer tester on the van an code came up as miss fire on #2. We changes the plug and plug wire, cleared code and ran code reader again. then code came up as miss fire on #2 and #6 cylinder. We have changed the plugs, plug wires, and the coil. what else could it be.,

My car has 227000 miles.
My car has an automatic transmission.

A: Hello. If the misfires are continuing to oc...

Hello. If the misfires are continuing to occur and the ignition parts are good then it may be a faulty fuel injector or an issue within the engine. I usually do a compression test first. By doing this I would know if the problem was internal such as a valve seat failure. If the compression test comes back fine then I test the injectors on those cylinder to make sure that are fine. If those happen to be good also then there is more than likely a problem within the circuit that is causing this and further diagnosis will need to be dine. If you need to have this misfire fixed, consider YourMechanic, as a certified mechanic can come to your home or office to diagnose and repair this.

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