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Q: My 2007 Grand Caravan has hard detonation problems.

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Grand Caravan hard detonation, noisy, lacks power, cannot drive over 30 mph because it starts to shake. Can hear and feel the detonation (cylinders, spark plugs). So far replaced the following parts: Spark plugs (Champion, gap 0.050) Spark plugs wires Ignition Coil Throttle Position Sensor Crankshaft Sensor Knock Sensor OBD II Scanner Codes indicated multiple cylinder misfire (1,3 and 4) Spark plug from 4th cylinder was burned. Vehicle doest not have a fuel filter, if it does, would be inside the tank, also doesnt have a fuel pressure regulator. I checked that info at Pepboys and Advanced Auto Parts websites. I poured a bottle of Cataclean in the tank. After two days poured two bottles of injector cleaner...nothing has changed. Any possibility that the injectors failed?

My car has 180000 miles.
My car has an automatic transmission.

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