Q: Van keeps blowing fuses, no lights in back work, can't shift unless key is in certain position

At first it started with not being able to shift from park to any other position. We replaced the brake light switch and it still didn't fix the problem. Noticed a fuse for the ignition was blown, so replaced the fuse. Worked for about three days and then the fuse blew again. When I replaced the fuse a second time, it lasted maybe a day. Now I blow a fuse Everytime I start the van. Also my headlights won't turn off and I don't even turn them on, turn signal lights in back won't work, brake lights and tail lights won't work, all bulbs are fine, gauges are sporadic and my fuel gauge goes to empty and fuel light comes on with half a tank of gas, still can't shift unless my van is off and key in certain position.

My car has 220000 miles.
My car has an automatic transmission.