Q: Hi James, engine lite on, cylinder misfire on 1, 3, 5, and 6. recently replaced all plugs and wires. question is does it do any go

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Hi James, engine lite on, cylinder misfire on 1, 3, 5, and 6. recently replaced all plugs and wires. question is does it do any good to replace say 5 and 6 immediately and the other two soon or am i wasting time? 5 and 6 are feasible to get to and do myself without removing manifold (Escape Ford 2004). basically am i doing any good or helping in replacing 2 of the 4 initiall? thanks for your time and any info

My car has 145000 miles.
My car has an automatic transmission.

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