Q: Cylinder #6 misfire on 4.0 liter SOHC

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I've replaced EGR plugs wires TPS idle control valve coil MAF sensor still show #6 misfire starts and runs but had vibration at 55 mph do u have an idea what this could be and has been wrong with similar vehicles cost to fix? Thanks Dan.

My car has 212000 miles.
My car has an automatic transmission.

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